epn

Best tactical approach to handling patients with simultaneous parasitic and HIV infection (Vol. 48, No. 5-6)

Cryptosporidiosis

New mathematical model for cryptosporidiosis - HIV co-infection explores their synergistic relationship in connection with prevention and treatment

One of the most common waterborne diseases worldwide is cryptosporidiosis, a parasitic disease affecting the small intestine and possibly our airways. It is a common cause of diarrhoea in HIV-positive patients, who are known to have lower immunity. Now the authors have developed a new model and numerical simulations to determine the optimal combination of prevention and treatment strategies for controlling both diseases in patients who have been co-infected. Their results, recently published, show a positive impact on the treatment and prevention for cryptosporidiosis alone, for HIV-AIDS alone, or for both together. They found that cryptosporidiosis preventions and treatment alone had no significant impact on reducing HIV-AIDS-related problems. By contrast, the prevention and treatment strategy for HIV-AIDS had a significant positive impact on the co-infected patients. Finally, applying both strategies at the same time resulted in reduction in all cases.

K.O. Okosun, M.A. Khan, E. Bonyah and S.T. Ogunlade, On the dynamics of HIV-AIDS and cryptosporidiosis, Eur. Phys. J. Plus 132, 363 (2017)
[Abstract]